SPINODYSSEY•Welcome

MEET AARON GOLDMAN, PhD
One of the Researchers YOU helped fund by Participating in
SPINODYSSEY 2012
AaronRsrchr

Aaron Goldman, PhD
Post Doctoral Research Fellow, Harvard Medical School
Division of Biomedical Engineering, Brigham and Women's Hospital
65 Landsdowne St. Cambridge, MA 02139

Breast cancer recurrence is often accompanied by the acquisition of
chemotherapy-resistance. We now know that within breast cancer, some cells are sensitive to chemotherapy while others resist treatment and regrow more aggressively than before. My research elucidates novel cellular processes which allow certain populations of breast cancer cells to tolerate the effects of chemotherapy. Using this knowledge, we engineer nano-scale therapeutics to specifically target chemotherapy tolerant breast cancer cells, prevent relapse and reduce the side-effects associated with treatment.

All the best, Aaron

THANKS TO YOU THE TOTAL WAS $311,334
RAISED FOR BREAST CANCER RESEARCH in SPINODYSSEY 2012

Online donation pages always stay open,
so more contributions are coming in every day!

http://www.active.com/donate/SpinOdyssey2012

You may still send checks to:

Susan Quaranta
American Cancer Society
38 Richards Ave.
Norwalk, CT 06854
800-889-3340

Support breast cancer patients at Whittingham Cancer Center
And patients in the Smilow Family Breast Health Center send checks to:

LINDA VERSEA
WHITTINGHAM CANCER CENTER
NORWALK HOSPITAL
MAPLE STREET, NORWALK, CT 06856

We will write in a day or two with the recap!

Great job everyone and keep the $$ coming!

We (ACS) pick our researchers April 11!

The SpinOdyssey Committee

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JUST IN CASE YOU DIDN'T GET A CHANCE TO
BUY THAT SPECIAL MOMENTO AT THE EVENT
YOU CAN BUY IT NOW HERE FROM OUR ONLINE
SPINODYSSEY STORE

here's a link to Tom Renner's storyon the daily norwalk

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CLICK THE ABOVE IMAGE TO GO DIRECTLY TO THE DEAL!

RETURNING SPONSORS

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_________________________

INTENSITY |490 westport avenue | norwalk | ct | 06851 | 203 853 7727

WATER BOTTLE SPONSOR

SPINODYSSEY 2011 - YOU RAISED $472,000

SPINODYSSEY 2011 AWARDED $649,000 to Douglas Hurst, Ph.D.
University of Alabama at Birmingham for his four year research titled:
"Composition of SIN3 protein complexes in breast cancer metastasis"

DougHurstSpin

"Words cannot begin to express my gratitude toward SPINODYSSEY 2011, and ACS for
funding my project. The pressure is now on us to produce meaningful results".

RESEARCH SYNOPSIS:
Metastasis is the major reason for morbidity and mortality of breast cancer patients. Every sequential step in the process of metastasis requires specific sets of genes to be turned on or off. These gene sets are regulated in part through large protein complexes that re-organize the structure of DNA and how it is interacting with associated proteins (chromatin). The current focus of our lab is to characterize the composition and enzyme activity of these chromatin modifying complexes that regulate the process of breast cancer metastasis. These studies will provide the necessary groundwork for the identification of novel targets to enable treatment of metastatic breast cancer.